Author

A. C. Gross

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

M. Cam· 4 shared M. V. Cannon· 4 shared R. D. Roberts· 4 shared S. Rajan· 2 shared A. M. Glaspell· 1 shared A. Oles· 1 shared B. E. Gryder· 1 shared B. J. Raphael· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCancer Biology

M. Cam

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Author profile →

4 papers

Recent·Most cited

Trabectedin Enhances Oncolytic Virotherapy by Reducing Barriers to Virus Spread and Cytotoxic Immunity in Preclinical Pediatric Bone Sarcoma

E. M. Ringwalt, M. A. Currier, A. M. Glaspell, C.-Y. Chen, M. V. Cannon, M. Cam, A. C. Gross, M. Gust, P.-Y. Wang, L. Boon, L. E. Biederman, E. Schwarz, P. Rajappa, D. A. Lee, E. R. Mardis, , T. P. Cripe

This study shows trabectedin enhances oncolytic virotherapy by reducing anti-viral barriers and boosting immune-mediated tumor regression in preclinical models.

bioRxiv · Mar 2, 2024Cancer Biology

Aberrant activation of wound healing programs within the metastatic niche facilitates lung colonization by osteosarcoma cells

J. B. Reinecke, L. Jimenez Garcia, A. C. Gross, M. Cam, M. V. Cannon, M. J. Gust, J. P. Sheridan, B. E. Gryder, R. Dries, R. D. Roberts

This study identifies fibrosis as a targetable vulnerability in osteosarcoma lung metastasis by showing nintedanib inhibits metastatic progression through anti-fibrotic effects.

bioRxiv · Jan 10, 2024Cancer Biology

Structurally complex osteosarcoma genomes exhibit limited heterogeneity within individual tumors and across evolutionary time

S. Rajan, S. Zaccaria, M. V. Cannon, M. Cam, A. C. Gross, B. J. Raphael, R. D. Roberts

This study analyzes SCNAs in osteosarcoma using single-cell DNA sequencing, finding limited heterogeneity and suggesting early catastrophic events drive genomic complexity.

bioRxiv · Aug 30, 2021Cancer Biology

Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

S. Rajan, E. Franz, C. A. McAloney, T. A. Vetter, M. Cam, A. C. Gross, C. Taslim, M. Wang, M. V. Cannon, A. Oles, R. D. Roberts

This study shows osteosarcoma tumors retain transcriptional heterogeneity during bone and lung colonization despite selective pressures.

bioRxiv · Nov 3, 2020 · PreprintCancer Biology