Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5
A. K. Kongsomboonvech, F. Rodriguez, A. L. Diep, B. M. Justice, B. E. Castallanos, A. Camejo, D. Mukhopadhyay, G. A. Taylor, M. Yamamoto, J. P. J. Saeij, M. L. Reese, K. Jensen
This study identifies NLRP3-dependent but inflammasome-independent pathways regulating CD8 T cell IFNγ responses to Toxoplasma gondii vacuolar antigens, independent of ROP5 virulence factors.
bioRxiv · Jan 20, 2020Immunology