Author

G. A. Taylor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. Murillo-Leon· 2 shared M. Yamamoto· 2 shared T. Steinfeldt· 2 shared A. Camejo· 1 shared A. F. Arenas Soto· 1 shared A. Gibson· 1 shared A. K. Kongsomboonvech· 1 shared A. L. Diep· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

M. Murillo-Leon

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dual role of Toxoplasma gondii ROP5 and ROP18 for NLRP3 inhibition

M. Murillo-Leon, A. M. Bastidas Quintero, S. Singh, X. Mueller, O. Gorka, B. Saller, A. F. Arenas Soto, C. Campos, J. E. Gomez-Marin, O. Gross, K. Pfeffer, J. C. Howard, G. A. Taylor, T. Steinfeldt

This paper identifies vacuolar disruption as a trigger for NLRP3 inflammasome activation in Toxoplasma gondii infection and shows ROP5 and ROP18 inhibit IL-1β release by protecting the parasitophorous vacuole and interacting with GBP5.

bioRxiv · Sep 17, 2023 · PreprintMicrobiology

IFN-lambda is protective against lethal oral Toxoplasma gondii infection

M. Murillo-Leon, A. M. Bastidas-Quintero, N. S. Endres, D. Schnepf, E. Delgado-Betancourt, A. Ohnemus, G. A. Taylor, M. Schwemmle, P. Staeheli, T. Steinfeldt

This study shows that IFN-lambda protects against lethal oral Toxoplasma gondii infection by enhancing intestinal epithelial and neutrophil responses.

bioRxiv · Feb 24, 2023 · PreprintImmunology

Crosstalk between enterocytes and innate lymphoid cells drives early IFN-g-mediated control of Cryptosporidium

J. Gullicksrud, A. Sateriale, J. B. Engiles, A. Gibson, S. Shaw, Z. Hutchins, L. Martin, D. A. Christian, G. A. Taylor, M. Yamamoto, D. P. Beiting, B. Striepen, C. Hunter

This study shows enterocytes promote ILC production of IFN-gamma, which restricts Cryptosporidium growth by acting on enterocytes themselves.

bioRxiv · Mar 13, 2021Immunology

Th17 immunity in the colon is controlled by two novel subsets of colon-specific mononuclear phagocytes

H.-I. Huang, M. L. Jewell, N. Youssef, M.-N. Huang, E. Hauser, B. E. Fee, N. P. Rudemiller, J. Privratsky, J. J. Zhang, E. Reyes, D. Wang, G. A. Taylor, M. D. Gunn, D. C. Ko, D. N. Cook, , G. E. Hammer

This study identifies two novel colon-specific mononuclear phagocyte subsets that are critical for Th17 immunity in the colon.

bioRxiv · Jan 28, 2021Immunology

Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5

A. K. Kongsomboonvech, F. Rodriguez, A. L. Diep, B. M. Justice, B. E. Castallanos, A. Camejo, D. Mukhopadhyay, G. A. Taylor, M. Yamamoto, J. P. J. Saeij, M. L. Reese, K. Jensen

This study identifies NLRP3-dependent but inflammasome-independent pathways regulating CD8 T cell IFNγ responses to Toxoplasma gondii vacuolar antigens, independent of ROP5 virulence factors.

bioRxiv · Jan 20, 2020Immunology