A. Donini

Bile Acids Serve As Endogenous Antagonists Of The Leukemia Inhibitory Factor (LIF) Receptor in Oncogenesis

The paper shows bile acids, specifically GDCA, inhibit LIFR in gastric cancer, suggesting potential for bile acid-based therapies in LIF-driven oncogenesis.

Next generation sequencing analysis of gastric cancer identifies the leukemia inhibitory factor receptor (LIFR) as a driving factor in gastric cancer progression and as a predictor of poor prognosis

This study identifies LIFR as a key driver in gastric cancer progression and a predictor of poor prognosis through RNA-seq analysis of patient samples.

Analysis of gastric cancer transcriptome allows the identification of histotype specific molecular signatures with prognostic potential

This study identifies histotype-specific molecular signatures in gastric cancer using transcriptomic analysis, finding AQP9, CARD14, and CXCR2 as prognostic markers.

Active transport of brilliant blue FCF across the Drosophila midgut and Malpighian tubule epithelia

The paper investigates whether Drosophila actively transport Brilliant blue FCF across midgut and Malpighian tubule epithelia under cold stress and finds they can mobilize the dye via an active transcellular pathway.

An impressive capacity for cold tolerance plasticity protects against ionoregulatory collapse in the disease vector, Aedes aegypti

This study shows that Aedes aegypti larvae and adults can acclimate to cold temperatures by maintaining ion balance, which may help them spread to colder regions.

Anti-diuretic activity of a CAPA neuropeptide can compromise Drosophila chill tolerance

This study shows that CAPA neuropeptide affects Drosophila chill tolerance by altering Malpighian tubule ion and water transport, with low doses impairing and high doses improving cold tolerance.

Functional Plasticity of the gut and the Malpighian tubules underlies cold acclimation and mitigates cold-induced hyperkalemia in Drosophila melanogaster

This study shows that cold acclimation in Drosophila improves chill tolerance by enhancing Malpighian tubule and gut ion transport, preventing cold-induced hyperkalemia without relying on ATPase activity changes.

Thermal Acclimation Mitigates Cold-Induced Paracellular Leak From The Drosophila Gut

The paper shows that cold exposure increases paracellular leak in Drosophila gut epithelia, but cold acclimation reduces this leak and improves cold tolerance.