Author

A. E. Cornish

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. J. Carr· 1 shared A. Y. Rudensky· 1 shared C. Edwards· 1 shared C. Konopacki· 1 shared D. Pe'er· 1 shared E. Azizi· 1 shared G. Plitas· 1 shared I. Malik· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. J. Carr

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Author profile →

2 papers

Recent·Most cited

Onco-Circuit Addiction and Onco-Nutrient mTORC1 Signaling Vulnerability in a Model of Aggressive T Cell Malignancy

X. Wang, A. E. Cornish, M. H. Do, J. S. Brunner, T.-W. Hsu, Z. Xu, I. Malik, C. Edwards, K. J. Capistrano, X. Zhang, M. H. Ginsberg, L. W. S. Finley, M. S. Lim, S. M. Horwitz, M. O. Li

The paper shows that mTORC1 signaling hypersensitivity to leucine drives an onco-circuit in T cell malignancy, and a low leucine diet is therapeutic without impairing T cell immunity.

bioRxiv · Apr 3, 2024 · PreprintCancer Biology

Single-cell Map of Diverse Immune Phenotypes Driven by the Tumor Microenvironment

E. Azizi, A. J. Carr, G. Plitas, A. E. Cornish, C. Konopacki, S. Prabhakaran, J. Nainys, K. Wu, V. Kiseliovas, M. Setty, K. Choi, R. M. Fromme, P. Dao, P. T. McKenney, R. C. Wasti, , D. Pe'er

The paper maps immune cell phenotypes in breast cancer using single-cell RNA-seq and identifies continuous tumor-specific expansions driven by environmental cues.

bioRxiv · Apr 2, 2018Immunology