Author

M. S. Lim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Wertheim· 2 shared A. De Martin· 1 shared A. E. Cornish· 1 shared A. Ferreira· 1 shared B. Austin· 1 shared B. Bhinder· 1 shared B. Ludewig· 1 shared B. T. Gaudette· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

G. Wertheim

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Onco-Circuit Addiction and Onco-Nutrient mTORC1 Signaling Vulnerability in a Model of Aggressive T Cell Malignancy

X. Wang, A. E. Cornish, M. H. Do, J. S. Brunner, T.-W. Hsu, Z. Xu, I. Malik, C. Edwards, K. J. Capistrano, X. Zhang, M. H. Ginsberg, L. W. S. Finley, M. S. Lim, S. M. Horwitz, M. O. Li

The paper shows that mTORC1 signaling hypersensitivity to leucine drives an onco-circuit in T cell malignancy, and a low leucine diet is therapeutic without impairing T cell immunity.

bioRxiv · Apr 3, 2024 · PreprintCancer Biology

A novel cryopreservation and biobanking strategy to study lymphoid tissue stromal cells in human disease

J. D. Brandstadter, A. De Martin, M. Lutge, A. Ferreira, B. T. Gaudette, Y. Stanossek, S. Wang, M. V. Gonzalez, E. Camiolo, G. Wertheim, B. Austin, D. Allman, M. S. Lim, D. C. Fajgenbaum, J. C. Aster, , I. Maillard

This study demonstrates that cryopreservation of lymphoid tissue allows for the study of non-hematopoietic stromal cells in human disease, preserving cell type proportions and transcriptional profiles.

bioRxiv · Feb 6, 2023Immunology

Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells

F. MAURA, B. Ziccheddu, J. J. Xiang, B. Bhinder, F. Abascal, K. Maclachlan, K. W. Eng, M. Uppal, F. He, W. Zhang, Q. Gao, V. Yellapantula, S. Park, M. Oberley, E. Ruckdeschel, , L. Giulino-Roth

This study uses whole genome sequencing of Hodgkin and Reed Sternberg cells to reconstruct the temporal evolution of classic Hodgkin lymphoma, identifying key mutations and structural variants.

bioRxiv · Nov 5, 2021Cancer Biology