Author

A. E. Ellis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

R. D. Sheldon· 2 shared R. J. House· 2 shared A. Johnson· 1 shared C. D. Capan· 1 shared C. D. Castello· 1 shared C. Isaguirre· 1 shared C. J. Essenburg· 1 shared C. R. Graveel· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

R. D. Sheldon

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A diverse proteome is present and enzymatically active in metabolite extracts

R. J. House, M. T. Soper-Hopper, M. P. Vincent, A. E. Ellis, C. D. Capan, Z. B. Madaj, E. Wolfrum, C. Isaguirre, C. D. Castello, A. Johnson, M. L. Escobar Galvis, K. Williams, H. Lee, R. D. Sheldon

The paper shows that metabolite extracts contain active enzymes and demonstrates a new workflow to remove proteins for improved metabolomics.

Nature Communications · Jul 10, 2024Peer-reviewedBiochemistry

NF1 deficiency drives metabolic reprogramming in ER+ breast cancer

R. J. House, E. A. Tovar, C. J. Essenburg, P. S. Dischinger, A. E. Ellis, I. Beddows, R. D. Sheldon, E. C. Lien, C. R. Graveel, M. R. Steensma

This study investigates how NF1 deficiency affects metabolic reprogramming in ER+ breast cancer and identifies potential therapeutic synergies between metabolic and targeted inhibitors.

bioRxiv · Nov 24, 2023 · PreprintCancer Biology