Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
R. J. House, M. T. Soper-Hopper, M. P. Vincent, A. E. Ellis, C. D. Capan, Z. B. Madaj, E. Wolfrum, C. Isaguirre, C. D. Castello, A. Johnson, M. L. Escobar Galvis, K. Williams, H. Lee, R. D. Sheldon
The paper shows that metabolite extracts contain active enzymes and demonstrates a new workflow to remove proteins for improved metabolomics.
Nature Communications · Jul 10, 2024Peer-reviewedBiochemistry
K. H. Sokol, C. J. Lee, T. J. Rogers, A. Waldhart, A. E. Ellis, S. Madireddy, S. R. Daniels, X. Ye, M. Olesnavich, A. Johnson, B. R. Furness, R. D. Sheldon, E. C. Lien
The paper shows lipid-starved cancer cells are more sensitive to ferroptosis due to increased PUFA trafficking into phospholipids, challenging the assumption that PUFA levels directly determine ferroptosis susceptibility.
bioRxiv · May 6, 2024Cancer Biology
K. R. Martin, S. L. Celano, R. D. Sheldon, R. G. Jones, J. P. MacKeigan
This study quantifies autophagy responses in single U2OS cells to amino acid and glucose starvation, finding that amino acid starvation induces autophagy while glucose starvation does not.
bioRxiv · Dec 1, 2023 · PreprintCell Biology
R. J. House, E. A. Tovar, C. J. Essenburg, P. S. Dischinger, A. E. Ellis, I. Beddows, R. D. Sheldon, E. C. Lien, C. R. Graveel, M. R. Steensma
This study investigates how NF1 deficiency affects metabolic reprogramming in ER+ breast cancer and identifies potential therapeutic synergies between metabolic and targeted inhibitors.
bioRxiv · Nov 24, 2023 · PreprintCancer Biology
E. H. Ma, M. S. Dahabieh, L. M. DeCamp, I. Kaymak, S. M. Kitchen-Goosen, D. G. Roy, M. J. Verway, R. M. Johnson, B. Samborska, C. A. Scullion, M. Steadman, M. Vos, T. P. Roddy, C. M. Krawczyk, K. S. Williams, , R. G. Jones
This study uses 13C-labeled metabolites to show CD8+ T cells switch from glutamine to acetate metabolism during infection.
bioRxiv · Jun 9, 2023 · PreprintImmunology
H. Guak, R. D. Sheldon, I. Beddows, A. Vander Ark, H. Shen, R. Jones, J. St. Pierre, E. Ma, C. M. Krawczyk
This study shows that PGC-1β promotes mitochondrial metabolism and suppresses inflammatory gene expression in dendritic cells.
bioRxiv · May 18, 2022Immunology
S. K. Gunasekar, L. Xie, P. R. Chheda, C. Kang, D. M. Kern, C. My-Ta, A. Kumar, J. M. Maurer, E. E. Gerber, W. J. Grzesik, M. Elliot-Hudson, Y. Zhang, C. A. Kulkarni, I. Samuel, J. K. Smith, , R. Sah
This study identifies small molecule modulators of the SWELL1-LRRC8 complex that improve glycemic control and prevent NAFLD in murine T2D by restoring insulin signaling and secretion.
Nature Communications · Feb 10, 2022Peer-reviewedPhysiology
P. F. Donald, J. Kamp, R. E. Green, R. Urazaliyev, M. Koshkin, R. D. Sheldon
This study identifies two migration routes of the Sociable Lapwing, reveals high site fidelity to stopover and wintering areas, and estimates the global population size while highlighting threats from hunting and habitat loss.
bioRxiv · Mar 31, 2020Ecology
S. Izreig, A. Gariepy, A. O. Donayo, G. Bridon, D. Avizonis, R. D. Sheldon, R. Laister, M. D. Minden, N. A. Johnson, K. S. Williams, M. S. Rudoltz, T. F. Duchaine, S. Yoo, M. N. Pollak, R. G. Jones
The paper shows that miR-17~92 expression in Myc+ tumors increases sensitivity to biguanide treatment by disrupting bioenergetic stability in lymphoma cells.
bioRxiv · Dec 20, 2019Cancer Biology