Transient T cell expansion, activation, and proliferation in therapeutically vaccinated SIV+ macaques treated with N-803
O. E. Harwood, A. J. Balgeman, A. J. Weaver, A. L. Ellis-Connell, A. M. Weiler, K. N. Erickson, L. M. Matschke, A. E. Golfinos, V. Vezys, P. J. Skinner, J. T. Safrit, P. T. Edlefsen, M. R. Reynolds, T. C. Friedrich, S. L. O'Connor
This study shows that therapeutic vaccination with a heterologous prime-boost regimen followed by N-803 treatment enhances CD8+ T cell responses in SIV-infected macaques.
bioRxiv · Jul 8, 2022 · PreprintImmunology