Author

A. E. Lord

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Olive· 1 shared C. Stephan-Otto Attolini· 1 shared G. E. Burkhart· 1 shared G. Ficz· 1 shared G. P. Huizinga· 1 shared H. A. von Recum· 1 shared J. Capellades· 1 shared J. D. Trombley· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. Olive

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Persister cancer cells are characterized by H4K20me3 heterochromatin that defines a low inflammatory profile

V. Ramponi, L. Richart, M. Kovatcheva, C. Stephan-Otto Attolini, J. Capellades, A. E. Lord, O. Yanes, G. Ficz, M. Serrano

This study identifies H4K20me3 heterochromatin in persister cancer cells, which reduces their inflammatory profile and reveals vulnerabilities in one-carbon metabolism.

bioRxiv · Jan 26, 2024 · PreprintCancer Biology

Simple degradable cyclodextrin polyester with chelator-based crosslinker for stent-based drug delivery

K. Young, A. E. Lord, G. E. Burkhart, S. K. Kozawa, N. Mu, H. A. von Recum

This paper develops a cyclodextrin polyester with a chelator-based crosslinker for stent-based drug delivery, showing controlled drug release and stable coating on metal stents.

bioRxiv · Apr 29, 2021 · PreprintBioengineering

A genome-wide screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation

M. C. Kiritsy, L. M. Ankley, J. D. Trombley, G. P. Huizinga, A. E. Lord, P. Orning, R. Elling, K. A. Fitzgerald, A. Olive

This study identifies new regulators of IFNγ-induced MHCII in macrophages using CRISPR screens, revealing pathways involving GSK3β and MED16 that are critical for CD4+ T cell activation.

bioRxiv · Aug 12, 2020Immunology