Author

C. Stephan-Otto Attolini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. Serrano· 3 shared M. Abad· 2 shared M. Kovatcheva· 2 shared N. Prats· 2 shared A. Berenguer· 1 shared A. Caballe· 1 shared A. E. Lord· 1 shared A. Garcia-Garijo· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

M. Serrano

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Author profile →

4 papers

Recent·Most cited

Persister cancer cells are characterized by H4K20me3 heterochromatin that defines a low inflammatory profile

V. Ramponi, L. Richart, M. Kovatcheva, C. Stephan-Otto Attolini, J. Capellades, A. E. Lord, O. Yanes, G. Ficz, M. Serrano

This study identifies H4K20me3 heterochromatin in persister cancer cells, which reduces their inflammatory profile and reveals vulnerabilities in one-carbon metabolism.

bioRxiv · Jan 26, 2024 · PreprintCancer Biology

Induction of senescence renders cancer cells highly immunogenic

I. Marin, O. Boix, A. Garcia-Garijo, i. Sirois, A. Caballe, E. Zarzuela, I. Ruano, C. Stephan-Otto Attolini, N. Prats, J. A. Lopez-Dominguez, M. Kovatcheva, E. Garralda, J. Munoz, E. Caron, M. Abad, , M. Serrano

This study shows that inducing senescence in cancer cells enhances their immunogenicity, leading to stronger anti-tumor immune responses compared to immunogenic cell death.

bioRxiv · Jun 5, 2022 · PreprintCancer Biology

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

D. Chondronasiou, D. Gill, L. Mosteiro, R. G. Urdinguio, A. Berenguer, M. Aguilera, S. Durand, F. Aprahamian, N. Nirmalathasan, M. Abad, D. E. Martin-Herranz, C. Stephan-Otto Attolini, N. Prats, G. Kroemer, M. F. Fraga, , M. Serrano

This study shows that a single cycle of transient OSKM expression reverses aging-related DNA methylation, transcriptional, and metabolic changes in multiple tissues of aged mice.

bioRxiv · Jan 20, 2022Cell Biology

Drosophila larval brain neoplasms present tumour-type dependent genome instability

F. Rossi, C. Stephan-Otto Attolini, J. L. Mosquera, C. Gonzalez

This study sequenced Drosophila tumours to assess genome instability, finding tumour-type dependent rates of SNPs and CNVs similar to human cancers.

bioRxiv · Sep 22, 2017Cancer Biology