Author

A. E. Spira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Sinjab· 2 shared B. Sepesi· 2 shared C. S. Stevenson· 2 shared E. Dai· 2 shared E. R. Parra· 2 shared G. Han· 2 shared H. Kadara· 2 shared I. I. Wistuba· 2 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Sinjab

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An atlas of epithelial cell states and plasticity in lung adenocarcinoma

G. Han, A. Sinjab, Z. Rahal, A. M. Lynch, W. Treekitkarnmongkol, Y. Liu, A. G. Serrano, J. Feng, K. Liang, K. Khan, W. Lu, S. Hernandez, Y. Liu, X. Cao, E. Dai, , H. Kadara

This study maps epithelial cell states and plasticity in lung adenocarcinoma using single-cell data, identifying KRT8+ alveolar intermediate cells linked to poor survival and tumorigenesis.

bioRxiv · May 13, 2022Cancer Biology

Resolving the spatial and cellular architecture of lung adenocarcinoma by multi-region single-cell sequencing

A. Sinjab, G. Han, W. Treekitkarnmongkol, K. Kobayashi, P. Brennan, M. Dang, D. Hao, R. Wang, E. Dai, H. Dejima, J. Zhang, E. Bogatenkova, B. Sanchez-Espiridion, K. Chang, D. R. Little, , H. Kadara

This study uses multi-region single-cell sequencing to map the spatial and cellular architecture of early-stage lung adenocarcinoma, revealing geospatial lineage evolution and potential therapeutic targets.

bioRxiv · Sep 4, 2020 · PreprintCancer Biology

Molecular Subtyping reveals Immune Alterations associated with Progression of Bronchial Premalignant Lesions

J. Beane, S. A. Mazzilli, J. D. Campbell, G. Duclos, K. Krysan, C. Moy, C. Perdomo, M. Schaffer, G. Liu, S. Zhang, H. Liu, J. Vick, S. S. Dhillon, S. J. Platero, S. M. Dubinett, , A. E. Spira

The paper identifies molecular subtypes of bronchial premalignant lesions and links immune alterations to their progression to lung cancer.

bioRxiv · Sep 12, 2018Cancer Biology