K. Liang

Non-destructive viability assessment of cancer cell spheroids using dynamic optical coherence tomography with trypan blue validation

This study validates dynamic optical coherence tomography as a quantitative viability assessment tool for 3D cancer cell spheroids using trypan blue exclusion as a reference.

hESCs-derived organoids achieve liver zonation by LSEC modulation

This study creates zonated liver organoids using hESCs-derived hepatocytes and LSECs, showing that GLP-1RA targets LSECs to alleviate NAFLD.

Enzyme Bioink for the 3D Printing of Biocatalytic Materials

This paper develops a biocatalytic enzyme bioink for 3D printing that enhances the biochemical activity of printed constructs by covalently attaching horseradish peroxidase to a gelatin methacrylate scaffold.

CZ CELLxGENE Discover: A single-cell data platform for scalable exploration, analysis and modeling of aggregated data

CZ CELLxGENE Discover provides a platform for scalable exploration and analysis of aggregated single-cell transcriptomic data across multiple studies.

Multi-scale tissue fluorescence mapping with fibre optic ultraviolet excitation and generative modelling

This paper introduces FUSE, a fibre optic microscopy technique with UV excitation and generative modelling for high-throughput cellular imaging of thick tissues, achieving sub-nuclear clarity and 3D topography.

Magnetic Levitation and Sorting of Neoplastic Circulating Cell Hybrids

This paper develops a magnetic levitation method to isolate neoplastic circulating hybrid cells from blood samples without surface marker dependence, demonstrating its feasibility for unbiased enrichment.

An atlas of epithelial cell states and plasticity in lung adenocarcinoma

This study maps epithelial cell states and plasticity in lung adenocarcinoma using single-cell data, identifying KRT8+ alveolar intermediate cells linked to poor survival and tumorigenesis.

Vibrio tarriae sp. nov., a novel member of the Cholerae clade isolated from across the United States

The paper describes the discovery and characterization of a novel Vibrio species, Vibrio tarriae, based on genetic, phylogenetic, and phenotypic analyses of isolates from the United States.

Near-atomic Structure of the Cytoplasmic Ring of the Xenopus laevis Nuclear Pore Complex

The paper presents near-atomic cryo-EM structures of the Xenopus laevis nuclear pore complex cytoplasmic ring, revealing its scaffold composition and organization.

Topological supramolecular network enabled highly conductive and stretchable organic bioelectronics

This paper introduces a topological supramolecular network strategy to create highly conductive and stretchable organic bioelectronics with unprecedented performance in physiological environments.

Wireless closed-loop smart bandage for chronic wound management and accelerated tissue regeneration

This paper develops a wireless smart bandage that monitors wound conditions and delivers electrical stimulation to accelerate tissue regeneration in chronic wounds.

Cryo-EM structure of the Inner Ring from Xenopus laevis Nuclear Pore Complex

The paper presents a cryo-EM structure of the inner ring subunit from Xenopus laevis NPC, revealing its composition and interactions.

Lin28a rejuvenates muscle stem cells via mitochondrial optimization

This study identifies Lin28a's role in rejuvenating muscle stem cells through mitochondrial optimization and epigenetic regulation, enhancing their regenerative capacity.