Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology
S. Zhang, Y. Zhu, J. Lu, z. Liu, A. G. Lobato, J. Liu, J. Qiang, W. Zeng, Y. Zhang, C. Liu, Z. He, G. zhai, D. Li
This study shows Hsp27 binds phosphorylated Tau to prevent its aggregation and mitigate AD pathology.
bioRxiv · May 8, 2022Biochemistry