Author

A. Gacser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:fungi (other)· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

C. Vagvolgyi· 3 shared R. Toth· 3 shared A. Szekeres· 2 shared J. D. Nosanchuk· 2 shared M. Horvath· 2 shared P. Horvath· 2 shared A. Szucs· 1 shared B. Szucs· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

C. Vagvolgyi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nicotinate degradation in a microbial eukaryote: a novel, complete pathway extant in Aspergillus nidulans

E. Bokor, J. Amon, M. Varga, A. Szekeres, Z. Hegedus, T. Jakusch, M. Flipphi, C. Vagvolgyi, A. Gacser, C. Scazzocchio, Z. Hamari

The paper identifies a complete eukaryotic nicotinate utilization pathway in Aspergillus nidulans, revealing novel metabolites and enzymes distinct from bacterial pathways.

bioRxiv · Aug 17, 2021 · PreprintMicrobiology

Candida albicans enhances the progression of oral squamous cell cancrinoma in vitro and in vivo

M. Vadovics, N. Igaz, R. Alfoldi, D. Rakk, E. Veres, B. Szucs, M. Horvath, R. Toth, A. Szucs, P. Horvath, L. Tiszlavicz, C. Vagvolgyi, J. Nosanchuk, A. Szekeres, M. Kiricsi, , A. Gacser

This study shows that C. albicans promotes OSCC progression in vitro and in vivo by inducing inflammation, oncometabolites, and metastatic gene expression.

bioRxiv · Mar 31, 2021 · PreprintMicrobiology

Oral epithelial cells distinguish between Candida species with high or low pathogenic potential through miRNA regulation

M. Horvath, G. Nagy, N. Zsindely, L. Bodai, P. Horvath, C. Vagvolgyi, J. D. Nosanchuk, R. Toth, A. Gacser

The paper shows oral epithelial cells respond differently to C. albicans and C. parapsilosis, with miRNA regulation playing a key role in distinguishing their pathogenic potential.

bioRxiv · Jan 23, 2021 · PreprintMicrobiology

Phagocytic predation by the fungivorous amoeba Protostelium aurantium targets metal ion and redox homeostasis

S. Radosa, J. L. Sprague, R. Toth, T. Wolf, M. Sprenger, S. Brunke, G. Panagiotou, J. Linde, A. Gacser, F. Hillmann

This study shows that the amoeba Protostelium aurantium targets fungal copper and redox homeostasis during predation, with gene deletions in C. parapsilosis confirming their role in survival against phagocytic killing.

bioRxiv · Jul 3, 2019 · PreprintMicrobiology

Candida auris: multi-omics signature of an emerging and multidrug-resistant pathogen

D. Zamith-Miranda, H. M. Heyman, L. G. Cleare, S. P. Couvillion, G. C. Clair, E. L. Bredeweg, A. Gacser, L. Nimrichter, E. S. Nakayasu, J. D. Nosanchuk

This paper compares multi-omics profiles of two Candida auris isolates and a Candida albicans reference strain to understand drug resistance and virulence mechanisms.

bioRxiv · Jan 23, 2019Microbiology