G. Nagy

A Reference Data Set for Circular Dichroism Spectroscopy Comprised of Validated Intrinsically Disordered Protein Models

The paper provides a reference dataset of validated intrinsically disordered protein models and their CD spectra to assess the accuracy of CD prediction tools.

Biomolecular condensates form spatially inhomogeneous network fluids

This study uses multiple techniques to characterize the structural properties of biomolecular condensates, revealing network fluid behavior with spatial inhomogeneities.

DNA Repair Function Scores for 2172 Variants in the BRCA1 Amino-Terminus

The paper presents functional scores for 2172 BRCA1 variants using a multiplexed HDR assay, showing 93% sensitivity and 100% specificity in classifying pathogenic and benign variants.

CotH genes are necessary for normal spore formation and virulence in Mucor lusitanicus

This study identifies CotH genes in Mucor lusitanicus and shows their role in spore formation, virulence, and cell wall structure through CRISPR-Cas9 disruption and infection models.

Dual RNA-Seq profiling unveils mycoparasitic activities of Trichoderma atroviride against haploid Armillaria ostoyae in antagonistic interaction assays

This study uses dual RNA-Seq to analyze the transcriptomes of Trichoderma atroviride and Armillaria ostoyae during their antagonistic interaction, revealing biocontrol mechanisms and defense responses.

Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel

The paper investigates how the ribosome exit tunnel drives the formation of a helical structure in the peptide VemP, leading to translational arrest.

Oral epithelial cells distinguish between Candida species with high or low pathogenic potential through miRNA regulation

The paper shows oral epithelial cells respond differently to C. albicans and C. parapsilosis, with miRNA regulation playing a key role in distinguishing their pathogenic potential.

Small-angle neutron scattering solution structures of NADPH-dependent sulfite reductase

The paper reports the first solution structures of sulfite reductase heterodimers using small-angle neutron scattering, showing how subunit binding and oxidation state affect conformation and electron transfer.

Implementation of a Bayesian Secondary Structure Estimation Method for the SESCA Circular Dichroism Analysis Package

The paper implements and evaluates a Bayesian secondary structure estimation method in the SESCA package, showing reduced uncertainty and improved accuracy for circular dichroism spectra with non-secondary structure contributions.

The Anti-histamine Azelastine, Identified by Computational Drug Repurposing, Inhibits SARS-CoV-2 Infection in Reconstituted Human Nasal Tissue In Vitro

This paper identifies azelastine, an anti-histamine drug, as a potential inhibitor of SARS-CoV-2 infection through computational repurposing and in vitro testing in human nasal tissue.

How Accurate Are Circular Dichroism Based Secondary Structure Estimates?

This study evaluates the accuracy of circular dichroism-based secondary structure estimates by analyzing experimental and synthetic data, identifying key sources of error and improving the SESCA package.

SESCA: Predicting Circular Dichroism Spectra from Protein Molecular Structures

SESCA predicts circular dichroism spectra from protein structures, outperforming existing methods with 50% smaller average deviation.