G. Panagiotou

tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.

This study shows that tRNA hypomodification in Aspergillus fumigatus leads to 5-fluorocytosine resistance through premature activation of a cross-pathway control system.

Sodium chloride in the tumor microenvironment enhances T-cell metabolic fitness and cytotoxicity

This study shows sodium chloride enhances CD8+ T-cell metabolic fitness and cytotoxicity, improving tumor cell killing in vitro and in vivo.

CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan

This study identifies galactosaminogalactan as the fungal ligand for CD56 on human NK cells, triggering antifungal responses and immune cell activation.

A global survey of host, aquatic, and soil microbiomes reveals shared abundance and genomic features between bacterial and fungal generalists

The paper identifies microbial generalists and specialists across host, soil, and aquatic environments, showing their ecological roles and genomic features.

Disruption of the Aspergillus fumigatus RNA interference machinery alters the conidial transcriptome.

This study investigates the role of RNA interference in Aspergillus fumigatus by analyzing genetic variation and functional outcomes of RNAi component knockouts.

Strain dynamics of specific contaminant bacteria modulate the performance of ethanol biorefineries

This study identifies specific contaminant bacteria that reduce ethanol fermentation efficiency and shows how their removal could significantly lower industry emissions.

Effects of agricultural fungicide use on Aspergillus fumigatus abundance, antifungal susceptibility, and population structure

This study examines the effects of agricultural fungicide use on Aspergillus fumigatus abundance, antifungal susceptibility, and population structure, finding low resistance rates and no significant genomic impact.

Horseshoe crab genomes reveal the evolutionary fates of genes and microRNAs after three rounds (3R) of whole genome duplication

The dynamic surface proteomes of allergenic fungal conidia

This study identifies dynamic surface and secreted proteins of Aspergillus fumigatus conidia under different conditions and compares them to other allergenic molds.

Phagocytic predation by the fungivorous amoeba Protostelium aurantium targets metal ion and redox homeostasis

This study shows that the amoeba Protostelium aurantium targets fungal copper and redox homeostasis during predation, with gene deletions in C. parapsilosis confirming their role in survival against phagocytic killing.