Author

A. Gangaev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Kvistborg· 2 shared A. Dopler· 1 shared A. Ribas· 1 shared B. Schilling· 1 shared C. Blank· 1 shared D. Philips· 1 shared D. Schadendorf· 1 shared E. A. Rozeman· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

P. Kvistborg

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2 papers

Recent·Most cited

An "alert state" ribosome population acts as a master regulator of cytokine mediated processes

A. Dopler, F. Alkan, Y. Malka, K. Hoefakker, O. I. Isaeva, M. Kerkhoff, A. Gangaev, J. Silva, S. Ramalho, L. Hoekman, M. Altelaar, R. van der Kammen, J. W. Yewdell, P. Kvistborg, W. J. Faller

The paper identifies an 'alert-state' ribosome subpopulation (ASRs) that regulates cytokine-mediated processes by preferentially translating key mRNAs involved in immune responses.

bioRxiv · Oct 17, 2023Immunology

Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response

A. Gangaev, E. A. Rozeman, M. W. Rohaan, D. Philips, S. Patiwael, J. H. van den Berg, A. Ribas, D. Schadendorf, B. Schilling, T. Shumacher, C. Blank, J. B. A. G. Haanen, P. Kvistborg

The paper shows PD-1 blockade in melanoma patients does not increase the breadth or magnitude of melanoma-reactive CD8 T cells in peripheral blood, suggesting PD-1 acts mainly at the tumor site.

bioRxiv · Dec 15, 2020Immunology