Author

K. Hoefakker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2

Frequent Co-Authors

A. A. de Waard· 2 shared A. H. de Ru· 2 shared M. L. M. Jongsma· 2 shared P. A. van Veelen· 2 shared R. M. Spaapen· 2 shared S. Bliss· 2 shared T. Verkerk· 2 shared A. Dopler· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. A. de Waard

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3 papers

Recent·Most cited

An "alert state" ribosome population acts as a master regulator of cytokine mediated processes

A. Dopler, F. Alkan, Y. Malka, K. Hoefakker, O. I. Isaeva, M. Kerkhoff, A. Gangaev, J. Silva, S. Ramalho, L. Hoekman, M. Altelaar, R. van der Kammen, J. W. Yewdell, P. Kvistborg, W. J. Faller

The paper identifies an 'alert-state' ribosome subpopulation (ASRs) that regulates cytokine-mediated processes by preferentially translating key mRNAs involved in immune responses.

bioRxiv · Oct 17, 2023Immunology

Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens

A. A. de Waard, T. Verkerk, K. Hoefakker, D. M. van der Steen, M. L. M. Jongsma, S. Bliss, A. H. de Ru, P. A. van Veelen, M. Griffioen, M. H. M. Heemskerk, R. M. Spaapen

The paper identifies TAP-independent antigen presentation in healthy cells using a T cell clone and highlights the need for comprehensive testing of healthy cell types to safely target antigens for immunotherapy.

bioRxiv · Jun 11, 2020Immunology

PAKC: A novel Panel of HLA class I Antigen presentation machinery Knockout Cells from the same genetic origin

A. A. de Waard, T. Verkerk, M. L. M. Jongsma, K. Hoefakker, S. Sethumadhavan, C. Gerke, S. Bliss, G. M. C. Janssen, A. H. de Ru, F. H. J. Claas, A. Mulder, R. Tampe, P. A. van Veelen, A. Halenius, R. M. Spaapen

The paper generates a panel of APM knockout cell lines to study HLA class I antigen presentation and its role in immune responses.

bioRxiv · Jan 24, 2020Immunology