SARS-CoV-2 requires acidic pH to infect cells
A. J. B. Kreutzberger, A. Sanyal, A. Saminathan, L.-M. Bloyet, S. Stumpf, Z. Liu, R. Ojha, M. T. Patjas, A. Geneid, G. Scanavachi, C. A. Doyle, E. Somerville, R. Bango Da Cunha Correira, G. Di Caprio, S. Toppila-Salmi, , T. Kirchhausen
This study shows SARS-CoV-2 requires acidic pH for membrane fusion and genome release, even after proteolytic cleavage by furin or TMPRSS2.
bioRxiv · Jun 9, 2022Microbiology