MicrobiologybioRxiv
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the pre-hairpin intermediate of the spike protein
DOI 10.1073/pnas.2210990119
Author
A. J. B. Kreutzberger
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2022 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 31 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- ImmunologybioRxivPreprint
Humanized antibody potently neutralizes all SARS-CoV-2 variants by a novel mechanism
S. Luo, J. Zhang, A. J. B. Kreutzberger…·F. W. Alt
The paper describes a humanized antibody, SP1-77, that neutralizes all SARS-CoV-2 variants by blocking membrane fusion instead of ACE2 receptor binding.
DOI 10.1101/2022.06.26.497634 - MicrobiologybioRxiv
SARS-CoV-2 requires acidic pH to infect cells
A. J. B. Kreutzberger, A. Sanyal, A. Saminathan…·T. Kirchhausen
This study shows SARS-CoV-2 requires acidic pH for membrane fusion and genome release, even after proteolytic cleavage by furin or TMPRSS2.
DOI 10.1073/pnas.2209514119 - MicrobiologybioRxiv
Synergistic block of SARS-CoV-2 infection by combined drug inhibition of the host entry factors PIKfyve kinase and TMPRSS2 protease
A. J. B. Kreutzberger, A. Sanyal, R. Ojha…·T. Kirchhausen
This study finds that combining apilimod and camostat mesylate or nafamostat mesylate significantly enhances inhibition of SARS-CoV-2 infection in vitro.
DOI 10.1128/jvi.00975-21 - BiophysicsbioRxivPreprint
Synaptotagmin-7 endows a population of chromaffin cell vesicles with enhanced calcium sensing and delayed content release properties
M. Bendahmane, A. J. B. Kreutzberger, A. Chapman-Morales…·A. Anantharam
This study shows that Syt-7 enhances calcium sensing and delays content release in chromaffin cell vesicles, sustaining secretion during prolonged stimulation.
DOI 10.1101/704205