Author

A. Gonzalez-Perez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:clustering· 2 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2

Frequent Co-Authors

N. Lopez-Bigas· 3 shared F. Muinos· 2 shared O. Pich· 2 shared A. Cortes-Bullich· 1 shared A. Di Genova· 1 shared A. Garcia de Herreros· 1 shared A. Gilg Soit Ilg· 1 shared A. Iturbide· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCancer Biology

N. Lopez-Bigas

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses

L. Mangiante, N. Alcala, A. Di Genova, A. Sexton-Oates, A. Gonzalez-Perez, A. Khandekar, E. Bergstrom, J. Kim, C. Giacobi, N. Le-Stang, S. Boyault, C. Cuenin, S. Tabone-Eglinger, F. Damiola, C. Voegele, , Meyer

This study identifies four sources of heterogeneity in MPM using multi-omic factor analysis, showing how genomic events shape molecular profiles and clinical behavior.

bioRxiv · Sep 27, 2021Cancer Biology

The evolution of hematopoietic cells under cancer therapy

O. Pich, A. Cortes-Bullich, F. Muinos, M. Pratcorona, A. Gonzalez-Perez, N. Lopez-Bigas

This study investigates how chemotherapy influences the mutation burden and clonal expansion in hematopoietic cells, finding that platinum-based drugs leave a mutational footprint while 5-FU does not.

bioRxiv · Oct 29, 2020Cancer Biology

In silico saturation mutagenesis of cancer genes

F. Muinos, F. Martinez-Jimenez, O. Pich, A. Gonzalez-Perez, N. Lopez-Bigas

This study uses in silico saturation mutagenesis to identify driver mutations in 568 cancer genes across 66 tumor types, revealing how mutation probability and selection influence observed variants.

bioRxiv · Jun 3, 2020Cancer Biology

Reduction of LOXL2-mediated H3K4 oxidation increases chromatin accessibility and promotes chemosensitivity of triple-negative breast cancer cells

J.P. Cebrià-Costa, L. Pascual-Reguant, A. Gonzalez-Perez, G. Serra-Bardenys, J. Querol, M. Cosín, G. Verde, R.A. Cigliano, W. Sanseverino, S. Segura-Bayona, A. Iturbide, D. Andreu, P. Nuciforo, C. Bernado-Morales, V. Rodilla, , S. Peiró

This study shows that reducing LOXL2-mediated H3K4 oxidation decreases chromatin compaction and increases chemosensitivity in triple-negative breast cancer cells.

bioRxiv · Sep 13, 2018 · PreprintCancer Biology

Cancer Genome Interpreter Annotates The Biological And Clinical Relevance Of Tumor Alterations

D. Tamborero, C. Rubio-Perez, J. Deu-Pons, M. P. Schroeder, A. Vivancos, A. Rovira, I. Tusquets, J. Albanell, J. Rodon, J. Tabernero, C. de Torres, R. Dienstmann, A. Gonzalez-Perez, N. Lopez-Bigas

The paper introduces a tool to annotate and interpret the biological and clinical relevance of tumor genomic alterations.

bioRxiv · Jun 21, 2017Cancer Biology