Author

A. Khandekar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Abbasi· 1 shared A. Di Genova· 1 shared A. E. Moor· 1 shared A. Gilg Soit Ilg· 1 shared A. Gonzalez-Perez· 1 shared A. M. Flanagan· 1 shared A. Poret· 1 shared A. S. M. Islam· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Abbasi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In vivo single-cell CRISPR uncovers distinct TNF-alphaprograms in clonal expansion and tumorigenesis

P. F. Renz, U. Ghoshdastider, S. Baghai Sain, F. Valdivia-Francia, A. Khandekar, M. Ormiston, M. Bernasconi, J. A. Kretz, M. Lee, K. Hyams, M. Forny, M. Pohly, X. Ficht, S. J. Ellis, A. E. Moor, A. Sendoel

This study uses in vivo single-cell CRISPR to identify distinct TNF-α programs in clonal expansion and tumorigenesis, showing their roles in epithelial transformation and tumor initiation.

bioRxiv · Jul 13, 2023 · PreprintCancer Biology

Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses

L. Mangiante, N. Alcala, A. Di Genova, A. Sexton-Oates, A. Gonzalez-Perez, A. Khandekar, E. Bergstrom, J. Kim, C. Giacobi, N. Le-Stang, S. Boyault, C. Cuenin, S. Tabone-Eglinger, F. Damiola, C. Voegele, , Meyer

This study identifies four sources of heterogeneity in MPM using multi-omic factor analysis, showing how genomic events shape molecular profiles and clinical behavior.

bioRxiv · Sep 27, 2021Cancer Biology

Signatures of copy number alterations in human cancer

C. D. Steele, A. Abbasi, A. S. M. Islam, A. Khandekar, K. Haase, S. Hames, M. Tarabichi, T. Lesluyes, A. M. Flanagan, F. Mertens, P. Van Loo, L. B. Alexandrov, N. Pillay

This paper identifies 19 copy number signatures in 9,873 cancers, explaining 93% of TCGA samples, and reveals diverse mechanisms underlying copy number alterations in human cancer.

bioRxiv · Apr 30, 2021Cancer Biology

Microridges are apical projections formed of branched F-actin networks that organize the glycan layer

C. S. Pinto, A. Khandekar, B. Rajasekaran, P. Kiesel, G. Pigino, M. Sonawane

The paper identifies microridges as apical projections composed of branched F-actin networks that organize the glycan layer in zebrafish epidermal cells.

bioRxiv · Jul 1, 2019Cell Biology