Author

J. Orlans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 2 Organism:Arabidopsis· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

D. de Sanctis· 3 shared S. Basu· 3 shared A. Grieco· 1 shared A. L. Pey· 1 shared A. M. Orville· 1 shared C. Sauter· 1 shared D. Housset· 1 shared E. Girard· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBiochemistry

D. de Sanctis

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Author profile →

3 papers

Recent·Most cited

The nucleating agent crystallophore induces instant protein crystallization

C. Sauter, D. Housset, J. Orlans, R. de Wijn, K. Rollet, S. Rose, S. Basu, P. Benas, J. Perez, D. de Sanctis, O. Maury, E. Girard

This paper demonstrates how the crystallophore TbXo4 accelerates protein crystallization, enabling high-quality crystals for serial crystallography methods.

bioRxiv · May 13, 2024Biophysics

Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations

A. Grieco, S. Boneta, J. A. Gavira, A. L. Pey, S. Basu, J. Orlans, D. de Sanctis, M. Medina, J. M. Martin Garcia

This study determines the structure of hNQO1 with NADH using serial crystallography and simulations, showing NADH binding stabilizes the protein and drives functional cooperativity through structural communication.

Protein Science · Mar 19, 2024Peer-reviewedBiochemistry

Droplet microfluidics for time-resolved serial crystallography

J. Stubbs, T. Hornsey, N. Hanrahan, L. Blay-Esteban, R. Bolton, M. Maly, S. Basu, J. Orlans, D. de Sanctis, J.-u. Shim, P. D. Shaw Stewart, A. M. Orville, I. Tews, J. West

This paper develops a droplet microfluidics approach to produce uniform crystals and enable rapid micromixing for time-resolved serial crystallography.

bioRxiv · Jan 12, 2024Biochemistry