Author

A. Guppy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1

Frequent Co-Authors

C. E. Veale· 1 shared D. Y. Chirgadze· 1 shared J. D. Maman· 1 shared L. Pellegrini· 1 shared M. L. Kilkenny· 1 shared N. J. Rzechorzek· 1 shared S. W. Hardwick· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

C. E. Veale

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1 paper

Recent·Most cited

Structural basis for the interaction of SARS-CoV-2 virulence factor nsp1 with Pol α - Primase

M. L. Kilkenny, C. E. Veale, A. Guppy, S. W. Hardwick, D. Y. Chirgadze, N. J. Rzechorzek, J. D. Maman, L. Pellegrini

This study reports the cryoEM structure of the SARS-CoV-2 nsp1-primosome complex, revealing how nsp1 interacts with the DNA polymerase-primase complex to disrupt immune responses.

bioRxiv · Jun 17, 2021 · PreprintBiophysics