Author

A. Hapeshi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. R. Waterfield· 6 shared C. S. Hernandez-Rodriguez· 2 shared G. Taylor-Joyce· 2 shared J. R. J. Healey· 2 shared L. Baillie· 2 shared P. Oyston· 2 shared S. Manoharan· 2 shared T. Brooker· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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6 shared papersMicrobiology

N. R. Waterfield

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Author profile →

6 papers

Recent·Most cited

Insight into the emerging insect to human pathogen Photorhabdus revealing geographic differences in immune cell tropism.

M. L. Addison, A. Hapeshi, E. Carter, Z. X. Wong, J. Connelly, N. R. Waterfield

This study compares the pathogenic activities of Photorhabdus asymbiotica isolates from different geographic regions, showing geographic differences in immune cell tropism and temperature-dependent infectivity.

bioRxiv · Aug 22, 2023 · PreprintMicrobiology

The influence of extrachromosomal elements in the anthrax cross-over strain Bacillus cereus G9241.

G. Taylor-Joyce, S. Manoharan, T. Brooker, C. S. Hernandez-Rodriguez, L. Baillie, P. Oyston, A. Hapeshi, N. R. Waterfield

This study examines how extrachromosomal elements in Bacillus cereus G9241 affect gene expression and spore formation at different temperatures.

bioRxiv · Jul 13, 2022 · PreprintMicrobiology

From cereus to anthrax and back again: The role of the PlcR regulator in the cross-over strain Bacillus cereus G9241

S. Manoharan, G. Taylor-Joyce, T. Brooker, C. S. Hernandez-Rodriguez, A. Hapeshi, V. Baldwin, L. Baillie, P. Oyston, N. R. Waterfield

This study investigates how Bacillus cereus G9241 exhibits temperature-dependent toxin production, switching between B. cereus and B. anthracis-like phenotypes through PlcR and AtxA regulation.

bioRxiv · Jul 6, 2022 · PreprintMicrobiology

Temperature restriction in entomopathogenic bacteria

A. Hapeshi, J. R. J. Healey, G. Mulley, N. R. Waterfield

This study identifies a gene locus responsible for temperature restriction in Photorhabdus bacteria, showing its role in limiting growth to temperatures below 37°C and its absence in human-pathogenic species.

bioRxiv · Jun 2, 2020Microbiology

Photorhabdus Virulence Cassettes: extracellular multi-protein needle complexes for delivery of small protein effectors into host cells.

I. Vlisidou, A. Hapeshi, J. R. J. Healey, K. Smart, G. Yang, N. R. Waterfield

This study identifies Pnf as a Rho-GTPase toxin delivered by Photorhabdus Virulence Cassettes (PVCs) to disrupt host cell cytoskeletons, showing PVCs function as long-range protein delivery systems.

bioRxiv · Feb 15, 2019 · PreprintMicrobiology

Iso-propyl stilbene: A life-cycle signal?

A. Hapeshi, J. M. Benarroch, D. J. Clarke, N. R. Waterfield

This study examines the phenotypic and transcriptomic response of Photorhabdus bacteria to exogenous IPS, revealing its role in quorum sensing, antibiotic competition, and symbiotic development.

bioRxiv · Dec 18, 2018Microbiology