Author

D. J. Clarke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

C. L. Mackay· 3 shared C. Piergentili· 3 shared J. Marles-Wright· 3 shared J. Ross· 3 shared K. J. Waldron· 3 shared D. He· 2 shared K. J. Gallagher· 2 shared Z. McIver· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiochemistry

C. L. Mackay

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Lipidomic analysis reveals differences in Bacteroides species driven largely by plasmalogens, glycerophosphoinositols and certain sphingolipids

E. Ryan, B. G. Pastor, L. A. Gethings, D. J. Clarke, S. A. Joyce

The paper compares lipid signatures of four Bacteroides species, identifying species-specific differences in plasmalogens, glycerophosphoinositols, and sphingolipids, and shows compensatory mechanisms in lipid biosynthesis.

bioRxiv · Aug 11, 2022 · PreprintMicrobiology

Pore dynamics and asymmetric cargo loading in an encapsulin nanocompartment

J. Ross, Z. McIver, T. Lambert, C. Piergentili, K. J. Gallagher, J. E. Bird, F. L. Cruickshank, P. James, E. Zarazua-Arvizu, L. E. Horsfall, K. J. Waldron, M. D. Wilson, C. L. Mackay, A. Basle, D. J. Clarke, J. Marles-Wright

The paper uses cryo-EM and HDX-MS to analyze an encapsulin nanocompartment, revealing asymmetric cargo loading and dynamic pore behavior.

bioRxiv · Apr 15, 2021Biochemistry

Dissecting the structural and functional roles of a vicinal iron-binding site in encapsulated ferritins

C. Piergentili, J. Ross, D. He, K. J. Gallagher, W. A. Stanley, L. Adam, C. L. Mackay, K. J. Waldron, D. J. Clarke, J. Marles-Wright

This study investigates the structural and functional role of a secondary iron-binding site in encapsulated ferritins using enzymatic assays, mass-spectrometry, and X-ray crystallography.

bioRxiv · Apr 28, 2020 · PreprintBiochemistry

Photorhabdus Dam methyltransferase overexpression impairs virulence of the nemato-bacterial complex in insects

A. Payelleville, D. Blackburn, A. Lanois, S. Pages, M. Cambon, N. Ginibre, D. J. Clarke, A. Givaudan, J. Brillard

This study shows that overexpressing the Dam methyltransferase in Photorhabdus luminescens reduces the virulence of the nemato-bacterial complex in insects.

bioRxiv · Feb 8, 2019Microbiology

Iso-propyl stilbene: A life-cycle signal?

A. Hapeshi, J. M. Benarroch, D. J. Clarke, N. R. Waterfield

This study examines the phenotypic and transcriptomic response of Photorhabdus bacteria to exogenous IPS, revealing its role in quorum sensing, antibiotic competition, and symbiotic development.

bioRxiv · Dec 18, 2018Microbiology

Conservation of the structural and functional architecture of encapsulated ferritins in bacteria and archaea

D. He, C. Piergentili, J. Ross, E. Tarrant, L. R. Tuck, C. L. Mackay, Z. McIver, K. J. Waldron, D. J. Clarke, J. Marles-Wright

The paper structurally and functionally characterizes two EncFtn proteins from different species, showing conserved structure and catalytic activity despite diverse environments.

bioRxiv · Sep 30, 2018Biochemistry