Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis
A. I. Wong, T. Beites, K. A. Planck, S. Li, N. C. Poulton, K. Rhee, D. Schnappinger, S. Ehrt, J. M. Rock
This study identifies cAMP as a key mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis by analyzing the role of the essential adenylate cyclase Rv3645.
bioRxiv · Jul 7, 2022Microbiology