Author

T. Beites

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. Schnappinger· 3 shared S. Ehrt· 3 shared A. I. Wong· 1 shared A. Jinich· 1 shared J. M. Rock· 1 shared K. A. Planck· 1 shared K. Rhee· 1 shared K. Y. Rhee· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

D. Schnappinger

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Author profile →

3 papers

Recent·Most cited

Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation

Y. Xu, S. Ehrt, D. Schnappinger, T. Beites

The paper investigates synthetic lethality in Mycobacterium tuberculosis by showing that simultaneous inactivation of Ndh-1 and Ndh-2 NADH dehydrogenases leads to bacterial death due to impaired NADH oxidation.

bioRxiv · Apr 10, 2023 · PreprintMicrobiology

Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

A. I. Wong, T. Beites, K. A. Planck, S. Li, N. C. Poulton, K. Rhee, D. Schnappinger, S. Ehrt, J. M. Rock

This study identifies cAMP as a key mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis by analyzing the role of the essential adenylate cyclase Rv3645.

bioRxiv · Jul 7, 2022Microbiology

Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection

T. Beites, R. S. Jansen, R. Wang, A. Jinich, K. Y. Rhee, D. Schnappinger, S. Ehrt

This study identifies EtfDMtb as an essential dehydrogenase for fatty acid β-oxidation in Mtb, showing that disrupting it kills the bacterium in vitro and in mice.

bioRxiv · Apr 19, 2021Microbiology