Author

A. J. Bryer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:structural biology· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:multiome· 1

Frequent Co-Authors

J. R. Perilla· 3 shared A. Deshpande· 1 shared A. Francis· 1 shared C. Aiken· 1 shared C. Torres· 1 shared I. Rousso· 1 shared J. A. Hadden· 1 shared J. E. Stone· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiophysics

J. R. Perilla

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Author profile →

3 papers

Recent·Most cited

Elasticity of the HIV-1 Core Facilitates Nuclear Entry and Infection

A. Deshpande, A. J. Bryer, J. R. Andino-Moncada, J. Shi, J. Hong, C. Torres, S. Harel, A. Francis, J. R. Perilla, C. Aiken, I. Rousso

This study shows that HIV-1 core elasticity is essential for nuclear entry and infection, with capsid-targeting drugs reducing elasticity and impairing infectivity.

PLOS Pathogens · Sep 11, 2024Peer-reviewedBiophysics

Performance efficient macromolecular mechanics via sub-nanometer shape based coarse graining

A. J. Bryer, J. R. Perilla

This paper introduces a transferable coarse graining method using unsupervised machine learning to create accurate coarse molecules for biomolecular simulations, demonstrating its effectiveness across various systems.

bioRxiv · Aug 28, 2022Biophysics

High-performance analysis of biomolecular containers to measure small-molecule transport, transbilayer lipid diffusion, and protein cavities

A. J. Bryer, J. A. Hadden, J. E. Stone, J. R. Perilla

The paper introduces a 3D ray casting method to classify space inside and outside biomolecular containers, enabling efficient analysis of small-molecule transport, lipid diffusion, and protein cavities in molecular dynamics simulations.

bioRxiv · Jul 13, 2019Biophysics