Author

A. J. Curwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

N. Brouwers· 3 shared V. Malhotra· 3 shared A. Nakano· 1 shared C. Burballa· 1 shared D. Cruz-Garcia· 1 shared G. A. Thun· 1 shared G. Cantero· 1 shared I. G. Gut· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

N. Brouwers

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Author profile →

3 papers

Recent·Most cited

The ulcerative colitis associated gene FUT8 regulates the quantity and quality of secreted mucins

G. Cantero, C. Burballa, Y. Ohkawa, T. Fukuda, Y. Harada, IBD Character Consortium, A. J. Curwin, N. Brouwers, G. A. Thun, J. Gu, I. G. Gut, V. Malhotra

This study shows that FUT8 regulates mucin secretion and viscoelastic properties, linking its dysfunction to ulcerative colitis pathogenesis.

bioRxiv · Nov 30, 2021Cell Biology

Building new compartments for unconventional protein secretion from the early and late Golgi membranes

A. J. Curwin, N. Brouwers, A. Nakano, K. Kurokawa, V. Malhotra

The paper identifies CUPS and TCUPS as compartments involved in unconventional protein secretion, showing their dynamics and relationship to the Golgi during starvation.

bioRxiv · Oct 22, 2021 · PreprintCell Biology

Reactive oxygen species (ROS) triggers unconventional secretion of antioxidants and Acb1

D. Cruz-Garcia, N. Brouwers, V. Malhotra, A. J. Curwin

The paper shows that starvation induces ROS production, which triggers the unconventional secretion of antioxidants and Acb1, aiding cell regrowth upon nutrient repletion.

Journal of Cell Biology · Mar 19, 2020Peer-reviewedCell Biology