Author

I. G. Gut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Evolutionary Biology· 2 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Research Focus:cell type annotation· 4 Approach:statistical model· 4 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2

Frequent Co-Authors

C. Moutinho· 2 shared D. Marchese· 2 shared H. Heyn· 2 shared J. C. Nieto· 2 shared M. Gut· 2 shared P. Lorden· 2 shared R. Massoni-Badosa· 2 shared S. Rashmi· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

C. Moutinho

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Whole genomes of the amazonian Cacajao reveal complex connectivity and fast differentiation driven by high environmental dynamism

N. Hermosilla-Albala, F. E. Silva, S. Cuadros-Espinoza, C. Fontsere, A. Valenzuela-Seba, M. Gut, J. L. Kelley, S. Ruibal-Puertas, P. Alentorn-Moron, A. Faella, E. Lizano, I. Farias, T. Hrbek, J. Valsecchi, I. G. Gut, , J. P. Boubli

The paper presents whole genome data from 48 uakari monkeys, revealing genetic differentiation between bald and black uakaris due to environmental factors.

bioRxiv · Jul 22, 2023 · PreprintEvolutionary Biology

Multi-organ single-cell transcriptomics of immune cells uncovered organ-specific gene expression and functions

M. Tsagiopoulou, S. Rashmi, S. A. Fernandez, J. C. Nieto, I. G. Gut

The paper analyzes immune cell transcriptomes across 14 human organs to identify organ-specific gene expression and functions.

bioRxiv · May 29, 2023Immunology

An Atlas of Cells in the Human Tonsil

R. Massoni-Badosa, P. Soler-Vila, S. Aguilar-Fernandez, J. C. Nieto, M. Elosua-Bayes, D. Marchese, M. Kulis, A. Vilas-Zornoza, M. M. Bühler, S. Rashmi, C. Alsinet, G. Caratu, C. Moutinho, S. Ruiz, P. Lorden, , H. Heyn

The paper creates a comprehensive cell atlas of the human tonsil using single-cell multi-omics data, identifying 121 cell types and uncovering regulatory mechanisms and disease-related changes.

bioRxiv · Jun 24, 2022Immunology

The ulcerative colitis associated gene FUT8 regulates the quantity and quality of secreted mucins

G. Cantero, C. Burballa, Y. Ohkawa, T. Fukuda, Y. Harada, IBD Character Consortium, A. J. Curwin, N. Brouwers, G. A. Thun, J. Gu, I. G. Gut, V. Malhotra

This study shows that FUT8 regulates mucin secretion and viscoelastic properties, linking its dysfunction to ulcerative colitis pathogenesis.

bioRxiv · Nov 30, 2021Cell Biology

A Single-Cell Tumor Immune Atlas for Precision Oncology

P. Nieto, M. Marc Elosua-Bayes, J. L. Trincado, D. Marchese, R. Massoni-Badosa, M. Salvany, A. Henriques, E. Mereu, C. Moutinho, S. Ruiz, P. Lorden, V. Chin, D. C. Kaczorowski, C.-L. Chan, R. Gallagher, , H. Heyn

The paper creates a single-cell tumor immune atlas using data from 217 patients and 13 cancer types to improve immune cell annotation and spatial mapping for precision oncology.

bioRxiv · Oct 26, 2020Cancer Biology

Genomic evidence for recurrent genetic admixture during domestication mediterranean olive trees (Olea europaea).

I. Julca, M. Marcet-Houben, F. Cruz, J. Gomez-Garrido, B. S. Gaut, C. M. Diez, I. G. Gut, T. S. Alioto, P. Vargas, T. Gabaldon

This study analyzes genomic data from olive trees to show genetic admixture during domestication and identifies selected genes related to stress response and development.

bioRxiv · Mar 28, 2020Evolutionary Biology

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

A. B. Brinkman, S. Nik-Zainal, F. Simmer, F. G. Rodriguez-Gonzalez, M. Smid, L. B. Alexandrov, A. Butler, S. Martin, H. Davies, G. Dominik, X. Zou, M. Ramakrishna, J. Staaf, M. Ringner, A. Sieuwerts, , H. G. Stunnenberg

The paper shows PMDs are hypervariable in breast cancer and drive CGI hypermethylation, but do not significantly repress cancer genes.

bioRxiv · Nov 15, 2018Cancer Biology