Author

A. J. Mannion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. F. Odell· 3 shared G. P. Cook· 3 shared P. F. Jones· 3 shared A. Taylor· 1 shared H. Zhao· 1 shared L. C. Matthews· 1 shared L. Holmgren· 1 shared O. Bergman· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

A. F. Odell

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pro- and anti-tumour activities of CD146/MCAM in breast cancer result from its heterogeneous expression and association with epithelial to mesenchymal transition

A. J. Mannion, A. F. Odell, S. M. Baker, L. C. Matthews, P. F. Jones, G. P. Cook

This study shows CD146/MCAM has both pro- and anti-tumour roles in breast cancer due to its heterogeneous expression and link to epithelial to mesenchymal transition.

Frontiers in Cell and Developmental Biology · Apr 17, 2023Peer-reviewedCancer Biology

The junctional mechanosensor AmotL2 regulates YAP promotor accessibility

A. J. Mannion, H. Zhao, Y. Zhang, Y. von Wright, O. Bergman, P. Saharinen, L. Holmgren

This study shows AmotL2 regulates YAP promoter accessibility through chromatin remodeling in endothelial cells under mechanical stress.

bioRxiv · Jan 13, 2023 · PreprintCell Biology

Negative regulation of p53 by the poliovirus receptor PVR is a target of a human cytomegalovirus immune evasion molecule

A. F. Odell, A. J. Mannion, P. F. Jones, G. P. Cook

The paper shows that HCMV evades immune surveillance by retaining PVR intracellularly, preventing p53 induction and allowing infected cells to avoid immune and p53-mediated detection.

bioRxiv · Jul 4, 2022 · PreprintCell Biology

CD99 regulates cancer cell transendothelial migration and endothelial cell function via CDC42 and actin remodelling

A. J. Mannion, A. F. Odell, A. Taylor, P. F. Jones, G. P. Cook

This study shows CD99 regulates cancer cell transendothelial migration and endothelial function through CDC42 and actin remodeling in breast and prostate cancer.

bioRxiv · Sep 8, 2019Cell Biology