Author

A. J. Perez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 4 Approach:microscopy & imaging analysis· 3 Research Focus:cell signaling & trafficking· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

H.-C. T. Tsui· 4 shared M. E. Winkler· 4 shared S. L. Shaw· 3 shared K. E. Bruce· 2 shared M. J. Boersma· 2 shared M. M. Lamanna· 2 shared A. Taguchi· 1 shared B. E. Rued· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersMicrobiology

H.-C. T. Tsui

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4 papers

Recent·Most cited

Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae

A. J. Perez, M. M. Lamanna, K. E. Bruce, M. A. Touraev, J. E. Page, S. L. Shaw, H.-C. T. Tsui, M. E. Winkler

This study identifies three types of single-molecule motions of PG synthesis proteins in Streptococcus pneumoniae, revealing zonal, circumferential movement of core elongasome proteins and distinct behaviors of aPBP1a and MpgA.

bioRxiv · Jan 10, 2024 · PreprintMicrobiology

Chromosomal Duplications of MurZ (MurA2) or MurA (MurA1), Amino Acid Substitutions in MurZ (MurA2), and Absence of KhpAB Obviate the Requirement for Protein Phosphorylation in Streptococcus pneumoniae D39

H.-C. T. Tsui, M. Joseph, J. J. Zheng, A. J. Perez, I. Manzoor, B. E. Rued, J. D. Richardson, P. Branny, L. Doubravova, O. Massidda, M. E. Winkler

The paper identifies genetic modifications in Streptococcus pneumoniae that bypass the need for protein phosphorylation by altering MurZ and MurA activity.

bioRxiv · Mar 26, 2023Microbiology

Organization of Peptidoglycan Synthesis in Nodes and Separate Rings at Different Stages of Cell Division of Streptococcus pneumoniae

A. J. Perez, M. J. Boersma, K. E. Bruce, M. M. Lamanna, S. L. Shaw, H.-C. T. Tsui, A. Taguchi, E. E. Carlson, M. S. VanNieuwenhze, M. E. Winkler

This paper investigates the spatial organization of peptidoglycan synthesis in Streptococcus pneumoniae during cell division, revealing distinct rings and nodes of transpeptidase activity and PBP localization.

bioRxiv · Sep 27, 2020Microbiology

Movement Dynamics of Divisome and Penicillin-Binding Proteins (PBPs) in Cells of Streptococcus pneumoniae

A. J. Perez, Y. Cesbron, S. L. Shaw, J. Bazan Villicana, H.-C. T. Tsui, M. J. Boersma, Z. A. Ye, Y. Tovpeko, C. Dekker, S. Holden, M. E. Winkler

This paper investigates FtsZ dynamics and its relationship to septal PG synthesis in Streptococcus pneumoniae, finding that FtsZ movement is continuous and independent of PG synthesis rate.

bioRxiv · Sep 27, 2018Microbiology