Author

A. J. Pollak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

A. C. Newton· 1 shared A. McNeilly· 1 shared C. A. Worby· 1 shared J. C. Xu· 1 shared J. E. Mayfield· 1 shared M. Bose· 1 shared P. Cauntay· 1 shared S. A. Burel· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. C. Newton

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2 papers

Recent·Most cited

Mechanism Driven Early Stage Identification and Avoidance of Antisense Oligonucleotides Causing TRL9 Mediated Inflammatory Responses in Bjab cells

A. J. Pollak, P. Cauntay, T. Machemer, S. Paz, S. Damle, S. P. Henry, S. A. Burel

The paper develops and validates a high-throughput Bjab cell assay to identify proinflammatory PS-ASOs by measuring Ccl22 mRNA levels, showing it replicates hPBMC assay results and provides mechanistic insights.

bioRxiv · Dec 12, 2021 · PreprintPharmacology & Toxicology

Ca2+-dependent liquid-liquid phase separation underlies intracellular Ca2+ stores.

J. E. Mayfield, A. J. Pollak, C. A. Worby, J. C. Xu, V. Tandon, M. Bose, A. McNeilly, S. Banerjee, A. C. Newton

The paper identifies Ca2+-dependent liquid-liquid phase separation in CASQ1, a Ca2+ binding protein in skeletal muscle, explaining Ca2+ buffering and storage mechanisms.

bioRxiv · Jul 6, 2021 · PreprintBiochemistry