Author

A. J. Sabnis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

T. G. Bivona· 2 shared A. Tulpule· 1 shared B. Barad· 1 shared B. W. Newton· 1 shared C. H. Earnshaw· 1 shared D. V. Allegakoen· 1 shared E. Chan· 1 shared E. Pazarentzos· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

T. G. Bivona

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Author profile →

2 papers

Recent·Most cited

The essential chaperone DNAJC17 activates HSP70 to coordinate RNA splicing and G2-M progression.

D. V. Allegakoen, K. Kwong, J. Morales, T. G. Bivona, A. J. Sabnis

This study identifies DNAJC17 as an essential JDP that activates HSP70 to regulate RNA splicing and G2-M progression through structural domains.

bioRxiv · Oct 25, 2023Cell Biology

Synthetic essentiality of metabolic regulator PDHK1 in PTEN-deficient cells and cancers

N. Chatterjee, E. Pazarentzos, G. Hrustanovic, L. Lin, E. Verschueren, J. R. Johnson, M. Hofree, J. J. Yan, V. Olivas, B. W. Newton, J. V. Dollen, C. H. Earnshaw, J. Flanagan, E. Chan, S. Asthana, , T. G. Bivona

The paper identifies PDHK1 as a synthetic-essential gene in PTEN-deficient cells and cancers, showing its upregulation drives aerobic glycolysis and correlates with poor patient survival.

bioRxiv · Oct 11, 2018Cancer Biology