Inactivation of Ppp1r15a minimises weight gain and insulin resistance during caloric excess in mice
V. Patel, G. Bidault, J. E. Chambers, S. Carobbio, A. J. T. Everden, C. Garces, L. E. Dalton, F. M. Gribble, A. Vidal-Puig, S. J. Marciniak
This study shows that mice lacking PPP1R15A gain less weight and have improved insulin sensitivity on a high-fat diet but not on standard diet.
bioRxiv · May 4, 2018Physiology