Author

A. J. Trewin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:rat· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. P. Wojtovich· 2 shared G. D. Wadley· 2 shared S. Lamon· 2 shared A. Almast· 1 shared A. Baldzizhar· 1 shared A. M. Amitrano· 1 shared A. S. Milliken· 1 shared B. J. Berry· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

A. P. Wojtovich

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Author profile →

4 papers

Recent·Most cited

Regulation of mitochondrial calcium uniporter expression and calcium signalling by lncRNA Tug1 in cardiomyocytes.

A. J. Trewin, K. L. Weeks, G. D. Wadley, S. Lamon

This study shows that lncRNA Tug1 regulates MCU expression and Ca2+ signaling in cardiomyocytes through CaMKII, affecting cardiac function.

bioRxiv · Jul 22, 2023Cell Biology

Purification of mitochondria from skeletal muscle tissue for transcriptomic analyses reveals localisation of nuclear-encoded non-coding RNAs

J. Silver, A. J. Trewin, S. Loke, L. Croft, M. J. Ziemann, M. Soria, H. Dillon, S. Nielsen, S. Lamon, G. D. Wadley

The paper develops a method to purify mitochondria from skeletal muscle tissue and identifies nuclear-encoded non-coding RNAs localized within mitochondria using transcriptomic analyses.

bioRxiv · Apr 27, 2022 · PreprintCell Biology

Quantification of reactive oxygen species production by the red fluorescent proteins KillerRed, SuperNova and mCherry.

J. O. Onukwufor, A. J. Trewin, T. M. Baran, A. Almast, T. H. Foster, A. P. Wojtovich

The paper quantifies ROS production rates of KillerRed, SuperNova, and mCherry using HPLC and SOSG, finding SuperNova has the highest O2*- and 1O2 quantum yields.

bioRxiv · Sep 20, 2019Biochemistry

Controlling the Mitochondrial Protonmotive Force with Light to Impact Cellular Stress Resistance

B. J. Berry, A. J. Trewin, A. S. Milliken, A. Baldzizhar, A. M. Amitrano, M. Kim, A. P. Wojtovich

This study introduces an optogenetic tool to increase the mitochondrial protonmotive force, demonstrating its role in stress resistance and metabolic outcomes.

bioRxiv · Aug 21, 2019Physiology