Author

A. S. Milliken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:metabolism & bioenergetics· 3 Assay:metabolomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

P. S. Brookes· 3 shared S. M. Nadtochiy· 2 shared A. Baldzizhar· 1 shared A. J. Trewin· 1 shared A. M. Amitrano· 1 shared A. P. Wojtovich· 1 shared B. J. Berry· 1 shared C. Kulkarni· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

P. S. Brookes

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Distinct effects of intracellular vs. extracellular acidic pH on the cardiac metabolome during ischemia and reperfusion.

A. S. Milliken, J. Ciesla, S. M. Nadtochiy, P. S. Brookes

This study investigates how intracellular and extracellular acidic pH affect cardiac metabolism during ischemia and reperfusion, finding distinct metabolic changes induced by each condition.

bioRxiv · Aug 17, 2022Biochemistry

Inhibiting succinate release worsens cardiac reperfusion injury by enhancing mitochondrial reactive oxygen species generation

A. S. Milliken, S. M. Nadtochiy, P. S. Brookes

This study shows that inhibiting succinate release during reperfusion increases mitochondrial ROS and worsens cardiac injury by promoting PT pore opening.

bioRxiv · Apr 27, 2022Biochemistry

Complex effects of pH on ROS from mitochondrial complex II driven complex I reverse electron transport challenge its role in tissue reperfusion injury

A. S. Milliken, C. Kulkarni, P. S. Brookes

The paper investigates how pH affects ROS production via mitochondrial complex II to complex I reverse electron transport during reperfusion injury and finds that ROS generation is insensitive to pH despite changes in mitochondrial respiration.

bioRxiv · Aug 31, 2020 · PreprintBiochemistry

Controlling the Mitochondrial Protonmotive Force with Light to Impact Cellular Stress Resistance

B. J. Berry, A. J. Trewin, A. S. Milliken, A. Baldzizhar, A. M. Amitrano, M. Kim, A. P. Wojtovich

This study introduces an optogenetic tool to increase the mitochondrial protonmotive force, demonstrating its role in stress resistance and metabolic outcomes.

bioRxiv · Aug 21, 2019Physiology