Author

A. J. Wierzba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A. E. Palmer· 2 shared D. Gryko· 2 shared D. Batan· 1 shared E. Braselmann· 1 shared J. T. Polaski· 1 shared J. Wheeler· 1 shared M. Chrominski· 1 shared R. Jimenez· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

A. E. Palmer

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2 papers

Recent·Most cited

Targeting riboswitches with beta-axial substituted cobalamins

S. R. Lennon, A. J. Wierzba, S. H. Siwik, D. Gryko, A. E. Palmer, R. T. Batey

This study investigates interactions between eleven cobalamin derivatives and three cobalamin riboswitches, showing plasticity and selectivity in RNA-ligand binding with potential for antibiotic development.

bioRxiv · Dec 25, 2022 · PreprintBiochemistry

Riboglow: a multicolor riboswitch-based platform for live cell imaging of mRNA and small non-coding RNA in mammalian cells

E. Braselmann, A. J. Wierzba, J. T. Polaski, M. Chrominski, Z. Holmes, S.-T. Hung, D. Batan, J. Wheeler, R. Parker, R. Jimenez, D. Gryko, R. T. T. Batey, A. E. Palmer

The paper introduces Riboglow, a multicolor riboswitch-based platform for live cell imaging of mRNA and small non-coding RNA in mammalian cells, showing it outperforms existing methods with a smaller RNA tag.

bioRxiv · Apr 9, 2018Biochemistry