Author

J. T. Polaski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

J. Gertz· 2 shared K. S. Osborne· 2 shared Z. Blanchard· 2 shared A. E. Palmer· 1 shared A. J. Wierzba· 1 shared A. L. Welm· 1 shared A. Ventura· 1 shared C. M. Rush· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

J. Gertz

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Author profile →

4 papers

Recent·Most cited

Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs

S. Arnesen, J. T. Polaski, Z. Blanchard, K. S. Osborne, A. L. Welm, R. M. O'Connell, J. Gertz

bioRxiv · Oct 7, 2022Cancer Biology

Characterization of a novel estrogen- and progesterone-responsive endometrial cancer cell line: HCI-EC-23

C. M. Rush, Z. Blanchard, J. T. Polaski, K. S. Osborne, K. Osby, J. M. Vahrenkamp, C.-H. Yang, D. H. Lum, C. R. Hagan, K. K. Leslie, M. A. Pufall, K. W. Thiel, J. Gertz

This paper introduces a new endometrial cancer cell line, HCI-EC-23, which responds to estrogen and progesterone, and shows it has similar estrogen-responsive gene regulation to Ishikawa cells.

bioRxiv · Aug 25, 2022Cancer Biology

The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma

J. T. Polaski, D. B. Udy, L. F. Escobar-Hoyos, G. Askan, S. D. Leach, A. Ventura, R. Kannan, R. K. Bradley

This study investigates UPF1 mutations in pancreatic adenosquamous carcinoma, finding they are likely non-pathogenic and not a common driver of the disease.

bioRxiv · Aug 14, 2020Cancer Biology

Riboglow: a multicolor riboswitch-based platform for live cell imaging of mRNA and small non-coding RNA in mammalian cells

E. Braselmann, A. J. Wierzba, J. T. Polaski, M. Chrominski, Z. Holmes, S.-T. Hung, D. Batan, J. Wheeler, R. Parker, R. Jimenez, D. Gryko, R. T. T. Batey, A. E. Palmer

The paper introduces Riboglow, a multicolor riboswitch-based platform for live cell imaging of mRNA and small non-coding RNA in mammalian cells, showing it outperforms existing methods with a smaller RNA tag.

bioRxiv · Apr 9, 2018Biochemistry