Intracellular FUS protein accumulation leads to cytoskeletal, organelle and cellular homeostasis perturbations
C. W. Chung, A. J. Zhou, I. Mela, A. D. Stephens, A. Miyashita, P. H. St George-Hyslop, C. F. Kaminski, T. Knowles, G. S. Kaminski Schierle
This study investigates how mutant FUS protein accumulation affects cytoskeletal, organelle, and cellular homeostasis, linking it to cellular aging and potential senescence mechanisms.
bioRxiv · Oct 4, 2022 · PreprintBiophysics