Author

A. Javelle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:mechanistic / dynamical model· 3 Assay:electrophysiology· 2 Approach:statistical model· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. Tamburrino· 4 shared P. A. Hoskisson· 4 shared u. zachariae· 4 shared A. Bizior· 2 shared G. Dias Mirandela· 2 shared G. Williamson· 2 shared M. Boeckstaens· 2 shared A. M. Marini· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersBiochemistry

G. Tamburrino

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Author profile →

4 papers

Recent·Most cited

A mechanistic switch from selective transporter to an ion channel impairs the filamentation signalling capability of ammonium transceptors in yeast

G. Williamson, A. S. Brito, A. Bizior, G. Tamburrino, G. D. Mirandela, T. Harris, P. A. Hoskisson, u. zachariae, A. M. Marini, M. Boeckstaens, A. Javelle

The paper shows that variations in the Twin-His motif of Amt-Mep transporters switch their function from selective transport to non-specific ion channel activity, impairing filamentation signaling in yeast.

bioRxiv · Aug 25, 2021 · PreprintMicrobiology

A two-lane mechanism for selective biological ammonium transport

G. Williamson, G. Tamburrino, G. Dias Mirandela, M. Boeckstaens, M. Bade, A. Pisliakov, C. M. Ives, E. Terras, A. Bizior, P. A. Hoskisson, A.-M. Marini, U. Zachariae, A. Javelle

The paper reveals a two-lane mechanism for selective ammonium transport in Amt/Mep/Rh transporters using electrophysiology, yeast complementation, and molecular dynamics simulations.

bioRxiv · Nov 20, 2019Biochemistry

Merging in-solution X-ray and neutron scattering data allows fine structural analysis of membrane-protein detergent complexes

G. Dias-Mirandela, G. Tamburrino, M. T. Ivanovic, F. M. Strnad, O. Byron, T. Rasmussen, P. A. Hoskisson, J. S. Hub, U. Zachariae, F. Gabel, A. Javelle

The paper combines SAXS and SANS data to analyze unlabeled membrane-protein detergent complexes, providing more detailed structural information than either method alone.

bioRxiv · May 20, 2018Biophysics

The lipid environment determines the activity of the E. coli ammonium transporter, AmtB

G. Dias Mirandela, G. Tamburrino, P. A. Hoskisson, U. Zachariae, A. Javelle

This study shows that phosphatidylglycerol binding to AmtB is essential for its activity and stabilizes its structure, revealing new binding sites and functional roles.

bioRxiv · Apr 17, 2018Biochemistry