Author

A. K. Best

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. E. Isakson· 2 shared L. J. DeLalio· 2 shared A. Islam· 1 shared A. M. Miller· 1 shared A. S. Keller· 1 shared A. S. Padilha· 1 shared C. A. Ruddiman· 1 shared C. Lechauve· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

B. E. Isakson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Endothelial alpha globin is a nitrite reductase

T. C. S. Keller, A. S. Keller, G. B. Broseghini-Filho, J. T. Butcher, H. R. Askew Page, A. Islam, Z. Y. Tan, L. J. DeLalio, C. Lechauve, S. D. Brooks, P. Sharma, K. Hong, W. Xu, A. S. Padilha, C. A. Ruddiman, , B. E. Isakson

This study shows endothelial alpha globin functions as a nitrite reductase to mediate hypoxia-induced vasodilation in resistance arteries.

bioRxiv · Feb 12, 2021Physiology

Endothelial pannexin 1 channels control inflammation by regulating intracellular calcium

Y. Yang, L. J. Delalio, A. K. Best, E. H. Macal, J. A. Milstein, I. Donnelly, A. M. Miller, M. McBride, X. Shu, M. Koval, B. E. Isakson, S. R. Johnstone

This study shows that endothelial pannexin 1 channels regulate inflammation by controlling intracellular calcium, which in turn affects IL-1β production and release.

bioRxiv · Sep 6, 2019Cell Biology