Author

S. R. Johnstone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. E. Isakson· 2 shared M. W. Sedovy· 2 shared A. Barnes· 1 shared A. K. Best· 1 shared A. M. Miller· 1 shared A. M. Soltisz· 1 shared A. Malek· 1 shared C. E. Willi· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersPhysiology

B. E. Isakson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Preserving endothelial integrity in human saphenous veins during preparation for coronary bypass surgery

M. W. Sedovy, X. Leng, F. Iqbal, M. C. Renton, M. Leaf, K. Roberts, A. Malek, W. S. Arnold, D. A. Wyatt, C. W. Choate, J. F. Rowe, J. W. Baker, S. R. Johnstone, M. Joseph

This study compares heparinized saline and blood solutions for preserving saphenous vein endothelium during coronary bypass graft preparation, finding blood better preserves endothelial integrity and reduces oxidative stress.

Journal of Vascular Research · Jan 12, 2024Peer-reviewedPhysiology

Vascular Endothelial Barrier Protection Prevents Atrial Fibrillation by Preserving Cardiac Nanostructure

L. Mezache, A. M. Soltisz, S. R. Johnstone, B. E. Isakson, R. Veeraraghavan

This study shows that protecting the vascular barrier by targeting Cx43 and Panx1 channels reduces atrial fibrillation episodes and preserves cardiac nanostructure.

bioRxiv · Jun 20, 2023Physiology

A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and is Differentially Regulated during Hypoxia and Aging

L. B. Payne, H. Abdelazim, M. Hoque, A. Barnes, Z. Mironovova, C. E. Willi, J. A. Darden, C. Houk, M. W. Sedovy, S. R. Johnstone, J. C. Chappell

This study identifies soluble PDGFRβ isoforms generated by pre-mRNA splicing in the healthy brain, showing increased levels with age and hypoxia.

bioRxiv · Feb 3, 2023 · PreprintCell Biology

Endothelial pannexin 1 channels control inflammation by regulating intracellular calcium

Y. Yang, L. J. Delalio, A. K. Best, E. H. Macal, J. A. Milstein, I. Donnelly, A. M. Miller, M. McBride, X. Shu, M. Koval, B. E. Isakson, S. R. Johnstone

This study shows that endothelial pannexin 1 channels regulate inflammation by controlling intracellular calcium, which in turn affects IL-1β production and release.

bioRxiv · Sep 6, 2019Cell Biology