Author

Z. Y. Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:microscopy & imaging analysis· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Shi· 3 shared L. Gan· 3 shared S. Cai· 3 shared A. G. Reidenbach· 1 shared A. Islam· 1 shared A. J. Noble· 1 shared A. K. Best· 1 shared A. M. E. Faust· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCell Biology

J. Shi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Diversity-oriented synthesis encoded by deoxyoligonucleotides

L. Hudson, J. W. Mason, M. V. Westphal, M. J. R. Richter, J. R. Thielman, B. K. Hua, C. J. Gerry, G. Xia, H. L. Osswald, J. M. Knapp, Z. Y. Tan, P. Kokkonda, B. I. C. Tresco, S. Liu, A. G. Reidenbach, , K. Briner

The paper describes the design, synthesis, and validation of a 3.7 million-member DNA-encoded library using diversity-oriented synthesis to enhance structural diversity for drug discovery.

bioRxiv · Oct 16, 2022Biochemistry

Heterogeneous non-canonical nucleosomes predominate in yeast cells in situ

Z. Y. Tan, S. Cai, A. J. Noble, J. K. Chen, J. Shi, L. Gan

This study uses cryo-ET to show that most nucleosomes in yeast cells are non-canonical, challenging previous assumptions about their structure.

bioRxiv · Apr 4, 2021Cell Biology

Endothelial alpha globin is a nitrite reductase

T. C. S. Keller, A. S. Keller, G. B. Broseghini-Filho, J. T. Butcher, H. R. Askew Page, A. Islam, Z. Y. Tan, L. J. DeLalio, C. Lechauve, S. D. Brooks, P. Sharma, K. Hong, W. Xu, A. S. Padilha, C. A. Ruddiman, , B. E. Isakson

This study shows endothelial alpha globin functions as a nitrite reductase to mediate hypoxia-induced vasodilation in resistance arteries.

bioRxiv · Feb 12, 2021Physiology

Macromolecular and cytological changes in fission yeast G0 nuclei

Z. Y. Tan, S. Cai, S. A. Paithankar, X. Nie, J. Shi, L. Gan

The paper compares transcription, histone acetylation, and macromolecular packing in proliferating and quiescent G0 fission yeast nuclei using cytological and biochemical methods.

bioRxiv · Jan 11, 2020Cell Biology

Cryo-ET reveals nucleosome reorganization in condensed mitotic chromosomes in vivo

S. Cai, C. Chen, Z. Y. Tan, Y. Huang, J. Shi, L. Gan

The paper uses cryo-ET to study nucleosome organization in fission yeast mitotic chromosomes, revealing cluster and megacomplex structures and explaining gene expression patterns during mitosis.

bioRxiv · Nov 24, 2017Cell Biology