Author

A. K. Efremov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

J. Yan· 3 shared A. D. Bershadsky· 2 shared M. P. Sheetz· 2 shared M. Yao· 2 shared A. Jégou· 1 shared B. Martinac· 1 shared D. Oh· 1 shared G. Romet-Lemonne· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

J. Yan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multistable mechanosensitive behavior of cell adhesion driven by actomyosin contractility and elastic properties of force-transmitting linkages.

P. Liu, Q. Wang, M. Yao, A. K. Efremov

This study develops a model to investigate how molecular heterogeneity in adhesion proteins affects cell adhesion, revealing multistability and feedback loops confirmed experimentally.

bioRxiv · Sep 4, 2023Biophysics

Nucleus size and its effect on the chromatin structure in living cells.

A. K. Efremov, L. Hovan, J. Yan

This study develops a theoretical framework to explore how nucleus size affects chromatin structure and DNA-protein interactions in living cells.

bioRxiv · Jul 27, 2021Biophysics

Mechanosensitive calcium signaling in filopodia

A. K. Efremov, M. Yao, M. P. Sheetz, A. D. Bershadsky, B. Martinac, J. Yan

This study shows that stretching forces trigger Ca2+ influx through L-type channels in filopodia, causing persistent Ca2+ oscillations that influence cell migration.

bioRxiv · Oct 21, 2020Cell Biology

Force dependence of filopodia adhesion: involvement of myosin II and formins

N. O. Alieva, A. K. Efremov, S. Hu, D. Oh, Z. Chen, M. Natarajan, H. T. Ong, A. Jégou, G. Romet-Lemonne, J. T. Groves, M. P. Sheetz, J. Yan, A. D. Bershadsky

This study investigates how forces affect filopodia adhesion, showing that myosin IIA and formins are essential for force-dependent adhesion and substrate preference.

bioRxiv · Jun 6, 2018 · PreprintCell Biology