Efflux-linked Accelerated Evolution of Antibiotic Resistance at a Population Edge
S. Bhattacharyya, M. Bhattacharyya, D. M. Pfannenstiel, A. K. Nandi, Y. Hwang, K. Ho, R. M. Harshey
The paper shows efflux promotes antibiotic resistance mutations by linking high efflux to reduced DNA repair, validated through a clinical resistome database and swarm experiments.
bioRxiv · Apr 1, 2022Microbiology