R. M. Harshey

Flagellar motor remodeling during swarming requires FliL

This study identifies FliL as essential for flagellar motor remodeling during swarming in diverse bacteria, showing conservation across species and a specific interaction with FliF.

Iron Memory in E. coli

This study shows E. coli remembers prior swarming experiences through iron levels, improving future swarming efficiency and affecting other behaviors like biofilm formation and antibiotic tolerance.

A Second Role for the Second Messenger Cyclic-di-GMP in E. coli: Arresting Cell Growth by Altering Metabolic Flow

This paper identifies a new role for c-di-GMP in E. coli where YfiN inhibits cell growth by altering metabolic flow, independent of its usual division inhibition function.

Efflux-linked Accelerated Evolution of Antibiotic Resistance at a Population Edge

The paper shows efflux promotes antibiotic resistance mutations by linking high efflux to reduced DNA repair, validated through a clinical resistome database and swarm experiments.

Remodeling of Chemotaxis is a Cornerstone of Bacterial Swarming

The paper shows that remodeling the chemotaxis pathway to reduce tumble bias and increase run duration is a common adaptation in swarming bacteria across multiple species.

Mu Transposition in the Absence of the Target-capture Protein MuB Reveals New Roles of MuB in Target Immunity and Target Selection, and Redraws the Boundaries of the Insular Ter Region of E. coli

This study shows Mu transposition can occur genome-wide without MuB, revealing MuB's role in cis-immunity and extending the insular Ter region boundaries in E. coli.

Necrosignaling: Cell death triggers antibiotic survival pathways in bacterial swarms

This study identifies necrosignaling as a mechanism where bacterial cell death enhances antibiotic survival in swarms by activating efflux pumps through AcrA-TolC interactions.