Author

A. K. Shalek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 19 Cancer Biology· 6 Microbiology· 4 Bioengineering· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 26 Research Focus:cell type annotation· 25 Organism:human· 22 Assay:scRNA-seq· 22 Research Focus:differential expression· 19 Research Focus:cell-cell communication· 11 Approach:statistical model· 10 Research Focus:gene regulatory network inference· 7

Frequent Co-Authors

M. H. Wadsworth· 10 shared J. Ordovas-Montanes· 8 shared T. K. Hughes· 6 shared B. Berger· 4 shared I. Fleming· 4 shared J. C. Love· 4 shared S. K. Nyquist· 4 shared S. W. Kazer· 4 shared

Activity by Year

2017-2024 · peak 13/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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10 shared papersImmunology

M. H. Wadsworth

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Author profile →

33 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 2, 2019

Highly Efficient, Massively-Parallel Single-Cell RNA-Seq Reveals Cellular States and Molecular Features of Human Skin Pathology

T. K. Hughes, M. H. Wadsworth, T. M. Gierahn…·A. K. Shalek

The paper introduces an improved scRNA-Seq protocol, Seq-Well S^3, which enhances transcript capture and gene detection efficiency, and applies it to study inflammatory skin diseases.

DOI 10.1101/689273

humanscRNA-seq

𝕏 PostBluesky

BioengineeringbioRxivJun 7, 2018

Linking single-cell measurements of mass, growth rate, and gene expression

R. J. Kimmerling, S. M. Prakadan, A. J. Gupta…·S. R. Manalis

This paper introduces a microfluidic platform that links single-cell biophysical measurements with scRNA-seq to study gene expression related to cell mass and growth rate.

DOI 10.1186/s13059-018-1576-0

mousescRNA-seq

𝕏 PostBluesky

ImmunologybioRxivNov 14, 2017

Reduced cellular diversity and an altered basal progenitor cell state inform epithelial barrier dysfunction in human type 2 immunity

J. Ordovas-Montanes, D. F. Dwyer, S. K. Nyquist…·A. K. Shalek

This study profiles single-cell RNA-seq data from human respiratory tissues to show reduced epithelial diversity and altered basal progenitor states in type 2 immunity-driven diseases.

DOI 10.1038/s41586-018-0449-8

humanscRNA-seq

𝕏 PostBluesky